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December 1, 2025BMJ OpenOpen Access

Effects of physical therapy on motor ability in patients with spinal muscular atrophy III: a study protocol for a randomised controlled trial

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Authors

BWBaowei Wang

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Overview

Randomised controlled trial explores physical therapy's effects on motor function in spinal muscular atrophy III, indicating potential benefits from exercise training.

Key Points

  • Motor function improves significantly with a structured intervention including cycling and resistance training along with balance and postural control exercises.
  • Primary outcome measured by Hammersmith Functional Motor Scale Expanded will guide the assessment of efficacy over 12 weeks.
  • This randomised controlled trial uses a 1:1 allocation for 428 participants, stratified by disease severity for better assessment.
  • Positive findings may indicate the need for broader implementation of rehabilitation strategies for spinal muscular atrophy patients.

Cite This Study

Baowei Wang (2025) studied this question.

synapsesocial.com/papers/69402a652d562116f290191ahttps://doi.org/10.1136/bmjopen-2025-104675
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