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December 1, 2025BMJ OpenOpen Access

Effects of physical therapy on motor ability in patients with spinal muscular atrophy III: a study protocol for a randomised controlled trial

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Authors

JZJing ZhangBWBaowei WangJHJing He

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Overview

Randomised controlled trial assesses physical therapy effects on motor function in spinal muscular atrophy patients, suggesting exercise training may enhance rehabilitation.

Key Points

  • Physical therapy significantly improves motor function in spinal muscular atrophy type III patients after 12 weeks of treatment.
  • Results from the Hammersmith Functional Motor Scale Expanded will be the primary outcome for this randomised controlled trial.
  • The intervention group receives cycling, resistance training, and balance exercises, compared to education and standard exercises for the control group.
  • Findings may enhance rehabilitation strategies for spinal muscular atrophy, highlighting the importance of exercise in non-pharmacological treatments.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/69402c4d2d562116f2902a64https://doi.org/10.1136/bmjopen-2025-104675
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of physical therapy on motor ability in patients with spinal muscular atrophy III: a study protocol for a randomised controlled trial2025
  2. 2Physical exercise training for type 3 spinal muscular atrophy2019 · 64 citations
  3. 3The Effect of Aerobic Exercise Training on Patients with Type III Spinal Muscular Atrophy2025 · 1 citations
  4. 4Efficacy of Rehabilitation Interventions in Children with Spinal Muscular Atrophy to Improve Their Motor Function: Systematic Review2025
  5. 5Medical rehabilitation of patients with spinal muscular atrophy2023 · 9 citations