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September 5, 2025Applied SciencesOpen Access

In-Vitro Dynamic Bioaccessibility and Bioavailability as Key Parameters for Rational Engineering of Novel Curcumin Delivery Systems

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Authors

JPJose Antonio Vellido PerezAMA. Martínez-Férez

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Overview

This research demonstrates improved bioavailability of curcumin in emulsions compared to oleogel, highlighting the role of bioaccessibility in food design.

Key Points

  • Bioavailable curcumin was significantly higher in emulsions, reaching about 20.2 ± 2.5%, indicating better absorption dynamics.
  • The oleogel system, while less bioaccessible, achieved 41.8 ± 1.8% bioavailable curcumin, showcasing efficiency post-release.
  • Using the dynamic SimuGIT system simulated the gastrointestinal release, providing insights into the curcumin delivery mechanisms.
  • The W1/Og/W2 emulsion was found to be superior for rapid release, emphasizing design implications for functional food systems.

Cite This Study

Perez et al. (2025) studied this question.

synapsesocial.com/papers/68bb3ef72b87ece8dc957aadhttps://doi.org/10.3390/app15179417
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