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September 5, 2025Open Access

How well does spirometry capture the symptom range in primary ciliary dyskinesia? — a cross–sectional national study

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Authors

YLYin Ting LamMKMirjam KollerLSLeonie D Schreck

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Overview

Cross-sectional national study reviews how spirometry measures respiratory symptoms in PCD patients, suggesting improvements are necessary.

Key Points

  • Self-reported wheeze and frequent shortness of breath were linked to lower FEV1 and FEV1/FVC in patients with primary ciliary dyskinesia.
  • In a national survey, 67% of invited patients completed the assessment, revealing significant associations impacting lung function.
  • The analysis examined the relationship between spirometric measurements and reported respiratory symptoms, adjusting for demographic factors.
  • Findings highlight that traditional spirometry fails to capture the full spectrum of respiratory morbidity in primary ciliary dyskinesia patients.

Cite This Study

Lam et al. (2025) studied this question.

synapsesocial.com/papers/68bb420d2b87ece8dc957ebbhttps://doi.org/10.1101/2025.08.26.25334463
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1International consensus guideline for reporting transmission electron microscopy results in the diagnosis of primary ciliary dyskinesia (BEAT PCD TEM Criteria)2020 · 165 citations
  2. 2Lung Function in Patients with Primary Ciliary Dyskinesia: A Cross-Sectional and 3-Decade Longitudinal Study2010 · 204 citations
  3. 3Lung function from school age to adulthood in primary ciliary dyskinesia2022 · 43 citations
  4. 4Respiratory symptoms of Swiss people with primary ciliary dyskinesia2022 · 12 citations
  5. 5Multiple breath washout in primary ciliary dyskinesia: a systematic review of the literature2025 · 7 citations