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March 1, 2026Frontiers in PediatricsOpen Access

Comparison of spirometry, impulse oscillometry, and multiple breath washout in children with primary ciliary dyskinesia

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Authors

UBUtku BatuSNSafaa NasrCYCansu Yılmaz Yeğit

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Overview

Cross-sectional study evaluates lung function tests in children with primary ciliary dyskinesia and healthy controls, indicating MBW's diagnostic advantage.

Key Points

  • This study aims to compare the effectiveness of spirometry, impulse oscillometry, and multiple breath washout in evaluating pulmonary function in children with primary ciliary dyskinesia.
  • Cross-sectional, prospective study design
  • Participants included children aged 6–18 years with primary ciliary dyskinesia and healthy controls
  • Conducted pulmonary function tests using spirometry, MBW, and IOS on the same day
  • Children with PCD showed significantly lower FEV1 percent predicted and FVC percent predicted
  • PCD was associated with higher measures of respiratory resistance and abnormal lung clearance index
  • Significant negative correlations were found between LCI 2.5% and other pulmonary function indices in PCD patients

Cite This Study

Batu et al. (2026) studied this question.

synapsesocial.com/papers/69a3d6eaec16d51705d2da7bhttps://doi.org/10.3389/fped.2026.1752410
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Spirometry, Impulse Oscillometry, and Lung Clearance Index in Children with Primary Ciliary Dyskinesia2024
  2. 2Comparing Multiple Breath Washout Parameters in a Matched Cohort of Children With Cystic Fibrosis and Primary Ciliary Dyskinesia2026
  3. 3Multiple Breath Washout in Primary Ciliary Dyskinesia: Potential for Lung Disease Monitoring2025 · 1 citations
  4. 4How well does spirometry capture the symptom range in primary ciliary dyskinesia? — a cross–sectional national study2025
  5. 5Prospective longitudinal measurements of N <sub>2</sub> multiple breath washout indices in primary ciliary dyskinesia2014