Mini-review highlights allopurinol's potential antihypertensive effects due to oxidative stress modulation and endothelial function.
Allopurinol, primarily used to treat gout, has shown potential as an antihypertensive agent due to its effects on oxidative stress and endothelial function. This agent is not typically used as a first-line treatment for hypertension; however, some studies have suggested that it may have potential antihypertensive effects. More research is needed to establish its efficacy and mechanisms in treating hypertension.
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Imeer et al. (2025) studied this question.
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