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Clinical and histopathological changes of some vital organs associated with intra-peritoneal experimental infection with Trypanosoma evansi in Guinea pigs

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Experimental infection with trypanosoma evansi shows severe clearest clinical signs in guinea pigs, indicating extensive organ damage.

Infection with trypanosoma evansi caused significant clinical signs in guinea pigs, including anaemia and emaciation.
Postmortem findings revealed severe organ changes such as splenomegaly and hepatomegaly, indicating a systemic impact.
Histopathological examination showed distinct damage, evidenced by vascular congestion and inflammatory cell infiltration in multiple organs.
The study underscores the serious health risks associated with protozoan diseases in livestock, demanding attention for prevention.

Abdullahi et al. (2025) studied this question.

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