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September 5, 2025Proceedings of the National Academy of Sciences of Belarus Medical seriesOpen Access

Association of umbilical cord blood and breast milk immune composition with allergic disease manifestation

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Authors

NTNatallia TsikhanSLS. A. LialikauMBMikhail Belevtsev

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Overview

Cohort study examines umbilical cord blood and breast milk immune profiles, revealing links to allergic diseases in children.

Key Points

  • Higher IgE levels in umbilical cord blood correlate with food allergy development in children, indicating potential immune programming.
  • Lower sIgA levels in breast milk were found among mothers whose children developed food allergies, linking immune composition to disease risk.
  • Children with atopic dermatitis showed higher intrauterine IgE exposure and IL-5 levels in breast milk during the first month post-birth.
  • This research highlights the significance of immune factors in early life as predictors of allergic disease development.

Cite This Study

Tsikhan et al. (2025) studied this question.

synapsesocial.com/papers/68bb46c36d6d5674bccfedc5https://doi.org/10.29235/1814-6023-2025-22-3-183-194
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