Directed Secondary C(sp³)–H Borylation by a Phenoxyimine Iridium Catalyst at Room Temperature

Here, we report that directed secondary C(sp3)–H borylation at room temperature was achieved by using phenoxyimine iridium complexes as catalysts. This reaction enables the introduction of a boryl group at the β position of a directing group, such as a pyridyl and pyrazolyl groups. Furthermore, it was indicated that the addition of a small amount of pinacolborane is important for the efficient generation of catalytically active species.