Butterfly-like Photoresponsive Cyclometalated Ir(III) complex: An Emergence of Future Cancer Therapeutic Agent

U Sreelekha; Rishav Das; Indrani Paramasivan Latha Laxmi; Nilmadhab Roy; R. B. Roy; Logesh Mathivathanan; Ramasamy Tamizhselvi; Rinku Chakrabarty; Priyankar Paira

doi:10.1039/d5dt01164g

January 1, 2025Dalton Transactions

Butterfly-like Photoresponsive Cyclometalated Ir(III) complex: An Emergence of Future Cancer Therapeutic Agent

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Key Points

The Ir(III) complex displays significant potential as an anticancer agent through photoinduced mechanisms.
Exhibiting high efficacy, the complexes are characterized as both Type I and Type II photosensitizers in PDT.
Innovative cyclometalated designs highlight the versatility and adaptiveness of these compounds for cancer therapy.
Further studies are needed to evaluate long-term effects and clinical applications of this novel drug strategy.

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Implication

This research demonstrates an anticancer agent using photoresponsive Ir(III) complexes, suggesting new PDT strategies.

Abstract

Herein, we report photoinduced 2,2’-bipyrimidine-based mono and binuclear cyclometalated Iridium (III) complexes as a future promising anticancer agent exhibiting the best efficiency as a Type I and Type II PDT...

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Sreelekha et al. (2025) studied this question.

synapsesocial.com/papers/68bb4d2d6d6d5674bcd01714 https://doi.org/10.1039/d5dt01164g

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Butterfly-like Photoresponsive Cyclometalated Ir(III) complex: An Emergence of Future Cancer Therapeutic Agent

Key Points

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Implication

Abstract

Discussion

Cite This Study

Butterfly-like Photoresponsive Cyclometalated Ir(III) complex: An Emergence of Future Cancer Therapeutic Agent

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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