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September 5, 2025Open Access

Comparative Efficacy of Antihypertensive Drugs for Primary Stroke Prevention–A Network Meta-Analysis of Randomized Controlled Trials

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Authors

DNDessy NataliaLPLeo Deddy PradiptaAAA Alamsyaputra

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Overview

Network meta-analysis reveals calcium channel blockers may reduce stroke risk in patients with hypertension.

Key Points

  • Calcium channel blockers show superior efficacy in reducing stroke risk for patients with hypertension.
  • Non-dihydropyridine CCB demonstrated the highest efficacy with RR 0.61 in the analysis.
  • A network meta-analysis of 43 RCTs involving 255,299 participants assessed drug class effectiveness.
  • The findings suggest individual patient profiles must be considered alongside efficacy in selecting treatment.

Cite This Study

Natalia et al. (2025) studied this question.

synapsesocial.com/papers/68bb4d2d6d6d5674bcd017a2https://doi.org/10.19166/lijn.v1i2.10286
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