Table S4 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Asael Roichman; Gabriela Reyes‐Castellanos; Ziqing Chen; Zihong Chen; Sarah J. Mitchell; Michael R. MacArthur; Akshada Sawant; Llewelyn Levett; Jesse R. Powers; Victoria Burgo; Maria Gomez-Jenkins; Maria Ibrahim; Xincheng Xu; Beianka Tomlinson; Xiang Hang; Eric G. Pamer; Yong Wei; Yibin Kang; Eileen White; Joshua D. Rabinowitz

doi:10.1158/0008-5472.30028697

Key Points

Dietary fiber lacks a consistent effect on immune checkpoint blockade efficacy across diverse murine tumor models.
Significant changes in taxa associated with the LC_In0 diet were observed, indicating potential shifts in immune response.
Observational analysis across murine tumor models highlights the need for more targeted dietary intervention studies.
These findings may enable researchers to better understand the relationship between diet and cancer treatment responses.

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Implication

Observational analysis finds no consistent effect of dietary fiber on immune checkpoint blockade in murine tumor models, suggesting limitations in dietary interventions.

Abstract

Taxa exhibiting significant changes relative to the LC_In0 diet

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Roichman et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd02884 https://doi.org/10.1158/0008-5472.30028697

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Table S4 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

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Implication

Abstract

Discussion

Cite This Study

Table S4 from Dietary Fiber Lacks a Consistent Effect on Immune Checkpoint Blockade Efficacy Across Diverse Murine Tumor Models

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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