Supplementary Methods S2 from 6-[(1,4-Naphthoquinone-2-yl)methyl]thio–Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer

Key Points

Liquid chromatography-tandem mass spectrometry reveals metabolites linked to new glucose conjugates for prostate cancer.
Detailed analysis shows that the naphthoquinone-glucose conjugates may selectively target cancerous cells.
This method, involving liquid chromatography, enables high-throughput detection of targeted metabolites.
These findings underscore the potential for novel therapeutic strategies in advanced prostate cancer management.

Liquid chromatography-tandem mass spectrometry identifies potential metabolites in prostate cancer, suggesting a useful diagnostic tool.

Supplementary Methods S2: Liquid chromatography−tandem mass spectrometry (LC-MS/MS)

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Busenbender et al. (2025) studied this question.

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