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September 2, 2025Open Access

Supplementary Figure S4 from 6-[(1,4-Naphthoquinone-2-yl)methyl]thio–Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer

Tobias Busenbender Dmitry N. Pelageev Jessica Hauschild Moritz Kaune Lukas Boeckelmann Christoph Krisp Mohamed E. Elsesy Alexandra Zielinski Thomas Mair Maria Riedner Ayham Moustafa Simone Venz Malte Kriegs Konstantin Hoffer Yuri E. Sabutski Ksenia L. Borisova Nadja Strewinsky Svetlana M. Kovach Ekaterina A. Khmelevskaya Hartmut Schlüter В. Ф. Ануфриев Derya Tilki Markus Graefen Wael Mansour Carsten Bokemeyer Sergey A. Dyshlovoy Gunhild von Amsberg

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Key Points

Prostate cancer cell lines show varying expression of GLUT-1 and GLUT-4 mRNA levels.
RT-qPCR indicated differential expression among tested prostate cancer cells.
The study employs a targeted approach using glucose conjugates to assess cancer treatment potential.
Findings highlight the importance of glucose transporters in the progression of prostate cancer.

Implication

Analysis reveals GLUT-1 and GLUT-4 mRNA levels in prostate cancer cell lines, suggesting targeted therapeutic potential.

Abstract

Supplementary Figure S4: Expression of GLUT-1 and GLUT-4 mRNA in different prostate cancer cell lines examined using RT-qPCR

Discussion

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Cite This Study

Busenbender et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd02981 https://doi.org/10.1158/1535-7163.30028670

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S5 from 6-[(1,4-Naphthoquinone-2-yl)methyl]thio–Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer2025
2Supplementary Figure S2 from 6-[(1,4-Naphthoquinone-2-yl)methyl]thio–Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer2025
3Supplementary Figure S1 from 6-[(1,4-Naphthoquinone-2-yl)methyl]thio–Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer2025
4Supplementary Figure S3 from 6-[(1,4-Naphthoquinone-2-yl)methyl]thio–Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer2025
5Supplementary Methods S1 from 6-[(1,4-Naphthoquinone-2-yl)methyl]thio–Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer2025

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Supplementary Methods S2 from 6-[(1,4-Naphthoquinone-2-yl)methyl]thio–Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer2025
Data from 6-[(1,4-Naphthoquinone-2-yl)methyl]thio–Glucose Conjugates, a Novel Targeted Approach for Advanced Prostate Cancer2025
Figure S11 from A Compound That Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer2024