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September 2, 2025Open Access

Supplemental Table S1 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals

Melanie K. Flores Jessica L. Janes Mirajul Islam Junxiang Wan Jiali Liu Romonia R. Reams Li‐Ming Su Kelvin Yen Hemal H. Mehta Allison Reagan Lauren E. Howard Emily Wiggins Adriana C. Vidal Stephen J. Freedland Pinchas Cohen

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Key Points

mtDNA copy number is a significant factor predicting prostate cancer risk in White individuals but not in Black individuals.
Analysis showed that only Whites with higher mtDNA copy numbers exhibited increased prostate cancer risk.
Study focused on mtDNA copy number assessments of individuals across racial groups, revealing notable differences.
Findings call for tailored cancer risk assessments considering racial differences in mtDNA copy number.

Implication

Findings highlight mtDNA copy number as a predictor for prostate cancer in White individuals, suggesting racial disparities in risk assessment.

Abstract

Supplemental Table S1 contains mtDNA copy numbers used in this study for Black and White individuals.

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Cite This Study

Flores et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd02955 https://doi.org/10.1158/1940-6207.30028909

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplemental Figure S2 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals2025
2Supplemental Figure S1 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals2025
3Supplemental Figure S4 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals2025
4Supplemental Table S2 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals2025
5Supplemental Table S3 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals2025

Supplemental Figure S3 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals2025
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