Supplemental Table S2 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals

Melanie K. Flores; Jessica L. Janes; Mirajul Islam; Junxiang Wan; Jiali Liu; Romonia R. Reams; Li‐Ming Su; Kelvin Yen; Hemal H. Mehta; Allison Reagan; Lauren E. Howard; Emily Wiggins; Adriana C. Vidal; Stephen J. Freedland; Pinchas Cohen

doi:10.1158/1940-6207.30028906

September 2, 2025Open Access

Supplemental Table S2 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals

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Key Points

Mitochondrial DNA copy number is a potent predictor of prostate cancer in white individuals, but not in black individuals.
Clinical assessments revealed significant differences in prostate cancer grade based on mitochondrial DNA levels and race.
In-depth demographic and clinical evaluations were conducted at the time of biopsy, showing stark race-based disparities.
This study highlights the need for tailored approaches in cancer prediction based on genetic factors across different racial groups.

Implication

Analysis shows mitochondrial DNA copy number may predict prostate cancer in white individuals, suggesting racial differences.

Abstract

Supplemental Table S2 shows demographic and clinical characteristics at the time of biopsy stratified by prostate cancer grade for all individuals and by race.

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Cite This Study

Flores et al. (2025) studied this question.

synapsesocial.com/papers/68bb4e016d6d5674bcd029a1 https://doi.org/10.1158/1940-6207.30028906

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Supplemental Table S2 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplemental Table S2 from Mitochondrial DNA Copy-Number Assessment Is a Potent Predictor for Prostate Cancer in White but Not Black Individuals

Key Points

Implication

Abstract

Discussion

Cite This Study

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