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September 5, 2025Open Access

Table S6 from Tumor-Specific MHC-II Activates CD4⁺ and CD8⁺ T Cells in Head and Neck Squamous Cell Carcinoma to Boost Immunotherapy Efficacy

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Activation of CD4 and CD8 T cells leads to enhanced immunotherapy efficacy.
Increased density of tsMHC-II correlates with favorable patient characteristics.
This research focuses on head and neck squamous cell carcinoma and its immunological response.
Findings highlight the potential for tsMHC-II in targeting T cells for better treatment.

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Observational analysis correlates tsMHC-II density with T cell activation in head and neck cancer, suggesting improved immunotherapy outcomes.

Correlation between patient characteristics and density of tsMHC-II.

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Zhang et al. (2025) studied this question.

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Observational analysis correlates tsMHC-II density with T cell activation in head and neck cancer, suggesting improved immunotherapy outcomes.

Correlation between patient characteristics and density of tsMHC-II.