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September 5, 2025Open Access

Table S1 from Tumor-Specific MHC-II Activates CD4⁺ and CD8⁺ T Cells in Head and Neck Squamous Cell Carcinoma to Boost Immunotherapy Efficacy

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Tumor-specific MHC-II activates both CD4 and CD8 T cells, improving immunotherapy outcomes.
Among 34 clinical trial patients, significant T cell activation was observed with MHC-II stimulation.
Employing an analysis of tumor samples, T cell activity was measured and reported in detail.
The findings suggest that enhancing T cell responses can significantly boost immunotherapy efficacy.

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Analysis of T cell activation in head and neck squamous cell carcinoma, indicating improved immunotherapy responses.

Baseline demographics of 34 clinical trial patients.

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Zhang et al. (2025) studied this question.

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Analysis of T cell activation in head and neck squamous cell carcinoma, indicating improved immunotherapy responses.

Baseline demographics of 34 clinical trial patients.