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September 10, 2025Discover OncologyOpen Access

Long non-coding RNA-based single and combination independent prognostic biomarkers for hepatocellular carcinoma

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Authors

LJLong‐Bin JengChina Medical UniversityHYHorng-Ren YangChina Medical UniversityCTChiao‐Fang TengChina Medical University

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Implication

Review identifies long non-coding RNA as crucial prognostic biomarkers for hepatocellular carcinoma, suggesting potential for improved patient outcomes.

Key Points

  • Long non-coding RNA biomarkers can improve prognosis prediction in hepatocellular carcinoma patients, potentially enhancing survival rates.
  • Evidence shows that alterations in expression levels of lncRNAs correlate with the progression of hepatocellular carcinoma and patient outcomes.
  • This review focuses on the validation of lncRNA biomarkers, either singularly or in combinations, as independent prognostic indicators in HCC.
  • Understanding the roles of oncogenes and tumor suppressor genes regulated by lncRNAs could lead to better therapeutic strategies for HCC.

Cite This Study

Jeng et al. (2025) studied this question.

synapsesocial.com/papers/68c182589b7b07f3a060f12ehttps://doi.org/10.1007/s12672-025-03309-1
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