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September 10, 2025Clinical and translational reports

Scutellaria baicalensis in cancer therapy: multidimensional mechanisms and therapeutic potential

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Authors

CACormac AsheEHEric HayesOregon National Primate Research Center

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Implication

This review demonstrates the anticancer potential of Scutellaria baicalensis flavonoids, suggesting new strategies against tumor heterogeneity and drug resistance.

Key Points

  • Scutellaria baicalensis compounds enhance immune surveillance and inhibit cancer cell proliferation.
  • Key flavonoids like baicalein and wogonin induce apoptosis and impair DNA repair mechanisms.
  • Preclinical studies reveal synergistic effects of Scutellaria baicalensis with convention Chemotherapy.
  • Combining traditional phytomedicine with modern pharmacological strategies offers a holistic cancer therapy approach.

Cite This Study

Ashe et al. (2025) studied this question.

synapsesocial.com/papers/68c183f09b7b07f3a060f972https://doi.org/10.58832/ctr.2025.6.6.4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Bioactive Flavonoids from Scutellaria baicalensis in Non-Small Cell Lung Cancer: Mechanistic Insights and Emerging Translational Perspectives2026 · 3 citations
  2. 2A Review of the Research Progress on the Anticancer Mechanisms of the Active Components Baicalin and Baicalein of Scutellaria baicalensis in Digestive System Tumors2026
  3. 3Research Progress of Scutellaria baicalensis in the Treatment of Gastrointestinal Cancer2024 · 12 citations
  4. 4The most recent progress of baicalein in its anti-neoplastic effects and mechanisms2024 · 32 citations
  5. 5Promising Anti‐Cancer Effects and Mechanisms of Baicalin and Baicalein in the Treatment of Oral Cancer: A Comprehensive Review2026