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September 3, 2025Open Access

Supplementary Figure S4 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer

Jennifer M. Finan Yifei Guo Alexandra Q. Bartlett Kevin Hawthorne Matthew Reyer Margaret Haerr Olayinka Lamikanra Hen Halamish Valerie Calvert Canping Chen Zheng Xia Emanuel F. Petricoin Rosalie C. Sears Katelyn T. Byrne Jonathan R. Brody

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Key Points

Extracellular vesicles promote endothelial cell remodeling in pancreatic cancer.
Findings reveal alterations in endothelial behavior due to HuR regulation.
Mouse model analysis provided insights into cellular interactions in cancer.
Research highlights potential therapeutic pathways for targeting pancreatic cancer.

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Implication

Research shows that HuR-regulated extracellular vesicles influence endothelial cell behavior, suggesting a role in pancreatic cancer.

Abstract

Additional mouse model staining.

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Cite This Study

Finan et al. (2025) studied this question.

synapsesocial.com/papers/68c183f09b7b07f3a060fa77 https://doi.org/10.1158/2767-9764.30038866

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S6 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
2Supplementary Figure S3 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
3Supplementary Figure S2 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
4Supplementary Figure S1 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
5Supplementary Figure S5 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025