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September 3, 2025Open Access

Supplementary Figure S2 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer

Jennifer M. Finan Yifei Guo Alexandra Q. Bartlett Kevin Hawthorne Matthew Reyer Margaret Haerr Olayinka Lamikanra Hen Halamish Valerie Calvert Canping Chen Zheng Xia Emanuel F. Petricoin Rosalie C. Sears Katelyn T. Byrne Jonathan R. Brody

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Key Points

Extracellular vesicles significantly promote endothelial cell remodeling in pancreatic cancer.
Key evidence includes imaging validation of EV import, indicating a direct impact on endothelial cells.
Methodologies included in vitro validation of extracellular vesicle behavior and their effects on cells.
Potential implications highlight the role of extracellular vesicles in cancer advancement and therapy.

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Implication

Validation of EV import imaging shows enhanced endothelial cell remodeling in pancreatic cancer.

Abstract

Validation of EV import imaging in vitro.

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Cite This Study

Finan et al. (2025) studied this question.

synapsesocial.com/papers/68c183f09b7b07f3a060fa6e https://doi.org/10.1158/2767-9764.30038872

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S3 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
2Supplementary Figure S6 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
3Supplementary Figure S1 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
4Supplementary Figure S5 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
5Supplementary Data 1 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025