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September 3, 2025Open Access

Supplementary Figure S3 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer

Jennifer M. Finan Yifei Guo Alexandra Q. Bartlett Kevin Hawthorne Matthew Reyer Margaret Haerr Olayinka Lamikanra Hen Halamish Valerie Calvert Canping Chen Zheng Xia Emanuel F. Petricoin Rosalie C. Sears Katelyn T. Byrne Jonathan R. Brody

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Key Points

Extracellular vesicles promote remodeling in endothelial cells, impacting pancreatic cancer progression.
In experiments, repeating extracellular vesicle treatments affected endothelial cell behavior, enhancing responses.
Analysis involves in vitro studies using different endothelial cell lines to validate results.
Findings highlight the role of extracellular vesicles in cancer biology and potential therapeutic strategies.

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Implication

In vitro analyses show extracellular vesicles affect endothelial cells, suggesting implications for pancreatic cancer research.

Abstract

Repeating in vitro EV treatments with an additional endothelial cell line.

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Cite This Study

Finan et al. (2025) studied this question.

synapsesocial.com/papers/68c183f09b7b07f3a060fa6f https://doi.org/10.1158/2767-9764.30038869

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S2 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
2Supplementary Figure S6 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
3Supplementary Figure S1 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
4Supplementary Data 3 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025
5Supplementary Data 1 from HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer2025