Case report illustrates enhanced diagnostic performance of 68Ga-FAPI-04 over 18F-FDG in splenic angiosarcoma, suggesting improved clinical management.
Primary splenic angiosarcoma is a rare, aggressive tumor, characterized by rapid metastasis and poor prognosis. Herein, we report a case of 18 F-FDG and 68 Ga-FAPI-04 PET/CT imaging in a 57-year-old man with primary splenic angiosarcoma. 68 Ga-FAPI-04 PET/CT presented much higher uptake in the lesions compared with 18 F-FDG PET/CT, showing better diagnostic performance. Our case demonstrated the characteristics of 68 Ga-FAPI-04 PET/CT in primary splenic angiosarcoma and suggested its potential as a more promising alternative to 18 F-FDG PET/CT for diagnosis and a useful tool for clinical management.
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Fang et al. (2025) studied this question.
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