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September 4, 2025Open Access

Supplementary Figure S3 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors

Min Wang Yanxing Chen Lin Tian Chenyi Wu Jiaying Chen Jiajia Hu Runjie Huang Yingnan Wang Jinling Zhang Xiaojun Ouyang Liqin Wang Ying Jin Qi Zhao Feng Wang Rui‐Hua Xu

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Key Points

Vascular normalization enhances antitumor efficacy when combined with HDAC inhibitors and immunotherapy.
The interaction between vascular conditions and treatment shows significant therapeutic potential for solid tumors.
Research highlights the importance of vascular abnormalization in improving treatment outcomes with HDAC inhibitors.
Understanding these mechanisms may lead to more effective cancer therapies and treatment combinations.

Implication

Findings show improved antitumor efficacy with vascular normalization in solid tumors, indicating potential treatment benefits.

Abstract

Vascular abnormalization is associated with the efficacy of HDAC inhibitor combined immunotherapy

Discussion

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Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c18c089b7b07f3a06148d0 https://doi.org/10.1158/2159-8290.30050805

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure S5 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
2Supplementary Figure S2 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
3Supplementary Figure S1 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
4Supplementary Figure S9 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
5Supplementary Figure S7 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025

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Supplementary Figure S6 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025
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Supplementary Figure S4 from Vascular Normalization Augments the Antitumor Efficacy of Combined HDAC Inhibitor with Immunotherapy in Solid Tumors2025