Literature review reveals benefits of multislice computed tomography for diagnosing coronary artery disease, suggesting safer alternatives to invasive angiography.
Coronary artery disease remains a leading cause of graft failure after heart transplantation (HT). Because the transplanted heart is denervated, graft ischemia is typically asymptomatic, necessitating annual screening to detect cardiac allograft vasculopathy (CAV), monitor established coronary lesions, and evaluate in‑stent restenosis. The need for annual invasive coronary angiography, along with its associated risks, including potentially life-threatening complications, underscores the need for safer, yet equally effective, noninvasive diagnostic alternatives for evaluating coronary pathology in heart transplant recipients. Multislice computed tomography coronary angiography (MSCT–CAG) has been successfully employed in the diagnosis of ischemic heart disease (IHD) for many years and is well-established as a noninvasive alternative to conventional coronary angiography. This makes it particularly relevant to investigate its applicability and effectiveness in the post-transplant setting.
No takes yet. Share an insight, caveat, or question.
Sapronova et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: