Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025

A review on silver nanoparticle formulation of cisplatin for lung cancer therapy

View Full Paper
Ask AI
Bookmark
Share

Authors

SMSohitha MulupuriMVMounika VuyyuruNTNavya Tokala

Discussion

Loading...

Member takes

Overview

This review highlights silver nanoparticles’ role in enhancing cisplatin delivery in lung cancer, suggesting improved efficacy and reduced toxicity.

Key Points

  • Cisplatin-loaded silver nanoparticles show enhanced pharmacokinetic behavior and sustained drug release.
  • Preclinical studies indicate significant cytotoxicity and reduced nephrotoxicity compared to free cisplatin.
  • The combination of cisplatin and silver nanoparticles enhances apoptosis and autophagy in resistant lung cancer cells.
  • Challenges such as nanoparticle stability and regulatory barriers may impact clinical translation of this approach.

Cite This Study

Mulupuri et al. (2025) studied this question.

synapsesocial.com/papers/68c192459b7b07f3a06167c3https://doi.org/10.70604/learnint.v2i2.78
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exploring the Potentials of Silver Nanoparticles in Overcoming Cisplatin Resistance in Lung Adenocarcinoma: Insights from Proteomic and Xenograft Mice Studies2025 · 4 citations
  2. 2Nanocarrier-mediated cancer therapy with cisplatin: A meta-analysis with a promising new paradigm2024 · 9 citations
  3. 3Silver Nanoparticles Specially Amplify the Anticancer Effects of Platinum-Based Drugs by Disrupting Cellular Nucleotide and Sulfur Homeostasis2026 · 1 citations
  4. 4Combination therapy of cisplatin and green silver nanoparticles enhances cytotoxicity and apoptosis in breast cancer cells2024 · 4 citations
  5. 5A COMPREHENSIVE REVIEW: PLATINUM BASED CHEMOTHERAPY IN LUNG CANCER2026