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September 10, 2025Open Access

Rising Obesity-Related Cardiovascular Mortality in the United States, 1999–2020: Accelerating Trends and Widening Disparities

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Authors

GSGaurav SharmaXi'an University of Architecture and TechnologySPSai Swetha PavuluriAll India Institute of Medical Sciences BhubaneswarSKSuhas Kataveni

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Overview

Analysis reveals increasing CVD mortality rates related to obesity in various populations, highlighting urgent needs.

Key Points

  • Cardiovascular disease mortality rates rose significantly in the U.S. from 1999 to 2020, driven by obesity.
  • Age-adjusted mortality rates increased from 2.75 to 8.36 per 100,000, with a notable acceleration post-2018.
  • National trends were analyzed using death certificates from the CDC WONDER database covering ages 15–84 years.
  • Findings emphasize the growing obesity-related CVD burden and highlight disparities by age, sex, and geography.

Cite This Study

Sharma et al. (2025) studied this question.

synapsesocial.com/papers/68c1954e9b7b07f3a0618a53https://doi.org/10.21203/rs.3.rs-7530128/v1
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Also Consider

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  1. 1Disparities in obesity-related cardiovascular-induced mortality trends in the U.S. of America over two decades2026
  2. 2Temporal Trends and Disparities in Cardiovascular Mortality Among Adults With Obesity in the United States From 1999 to 20232026
  3. 3Concomitant mortality trends due to obesity and hypertension in the U.S.: a 20-year retrospective analysis of the CDC WONDER database2025 · 15 citations
  4. 4Trends and Disparities in Coronary Artery Disease and Obesity‐Related Mortality in the United States From 1999–20222024 · 25 citations
  5. 5Trends and Disparities in Obesity‐Related Mortality Among U.S. Adults: A CDC WONDER Analysis (1968–2025)2026