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Transcriptional profiling identifies unique molecular mechanisms in Crohn's disease phenotypes, suggesting behavior-driven differences.
Introduction: Crohn's disease (CD) presents with different behavioral phenotypes: non-stricturing/non-penetrating (B1), stricturing (B2), and stricturing/penetrating (B3). Whether these phenotypes are purely clinical or underpinned by distinct molecular mechanisms remains unclear.
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Lehmann et al. (2025) studied this question.
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