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September 10, 2025Diseases of the Esophagus

Outcomes Following Pathological Complete Response After Neoadjuvant Treatment in Patients With Oesophageal Cancer

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Patients achieving pathological complete response had a median overall survival of 58 months, indicating favorable long-term outcomes.
Among 235 patients, 78 (33%) achieved pathological complete response after neoadjuvant therapy, showing a trend toward better survival.
Postoperative morbidity occurred in 53% of patients, highlighting possible surgical risks despite the benefits of treatment.
Recurrence was observed in 8 patients, with a median time to recurrence of 12.5 months, highlighting the need for ongoing monitoring.

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Implication

Retrospective analysis shows improved survival outcomes in patients with pathological complete response, indicating the impact of neoadjuvant therapy.

Cite This Study

Thambudorai et al. (2025) studied this question.

synapsesocial.com/papers/68c195559b7b07f3a0618f65 https://doi.org/10.1093/dote/doaf061.179

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Implication

Retrospective analysis shows improved survival outcomes in patients with pathological complete response, indicating the impact of neoadjuvant therapy.

Outcomes Following Pathological Complete Response After Neoadjuvant Treatment in Patients With Oesophageal Cancer

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Discussion

Implication

Cite This Study

Outcomes Following Pathological Complete Response After Neoadjuvant Treatment in Patients With Oesophageal Cancer

Key Points

Discussion

Implication

Cite This Study

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