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September 10, 2025MedicineOpen Access

Investigating bidirectional causality between prostate cancer and inflammatory factors: A 2-sample Mendelian randomization analysis

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Authors

JWJieyan WangSouthern Medical UniversityQCQi ChengSouthwest UniversityFLFangyu LuoChinese Academy of Medical Sciences & Peking Union Medical College

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Overview

Mendelian randomization analysis reveals links between inflammatory cytokines and prostate cancer, suggesting risk factors and causal relationships.

Key Points

  • The research indicates a causal relationship between inflammatory cytokines and prostate cancer.
  • Results show that Flt3L and MCP4 may act as risk factors for the incidence of prostate cancer.
  • This analysis utilized Mendelian randomization methods to assess the genetic influence of inflammatory factors.
  • Findings point to the significance of inflammatory factors in prostate cancer progression and susceptibility.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c1955c9b7b07f3a0619378https://doi.org/10.1097/md.0000000000044180
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  5. 5The causal effect of cytokine cycling levels on the risk of cervical cancer: A bidirectional 2-sample Mendelian randomization study2026