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September 10, 2025Addiction BiologyOpen Access

Increased Mesostriatal Intrinsic Connectivity Associated With Cue Exposure in Adult Cannabis Users: Preliminary Findings

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Authors

NKNatalia M. KleinhansUniversity of Washington GTGarth E. TerryUniversity of Washington DKDahyeon KangUniversity of Washington

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Implication

Preliminary findings indicate altered VTA-striatal connectivity associated with cue exposure and craving in cannabis users, suggesting relapse vulnerability.

Key Points

Following cue exposure, cannabis users exhibited increased VTA-caudate connectivity, suggesting altered neural pathways.
Baseline craving was positively correlated with VTA-striatal connectivity in cannabis users before and after cue exposure.
No significant connectivity differences were observed at baseline between cannabis users and controls.
Findings suggest a neural mechanism linking cue exposure to relapse vulnerability in those with problematic cannabis use.

Cite This Study

Kleinhans et al. (2025) studied this question.

synapsesocial.com/papers/68c19f9154b1d3bfb60daf2f https://doi.org/10.1111/adb.70067

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Implication

Preliminary findings indicate altered VTA-striatal connectivity associated with cue exposure and craving in cannabis users, suggesting relapse vulnerability.

Increased Mesostriatal Intrinsic Connectivity Associated With Cue Exposure in Adult Cannabis Users: Preliminary Findings

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Implication

Key Points

Cite This Study

Increased Mesostriatal Intrinsic Connectivity Associated With Cue Exposure in Adult Cannabis Users: Preliminary Findings

Discussion

Member takes

Implication

Key Points

Cite This Study

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