Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Smart MedicineOpen Access

Identification of Differential Metabolites in Chronic Suppurative Otitis Media With Non‐Targeted and Targeted Metabolomics Approach

View Full Paper
Ask AI
Bookmark
Share

Authors

LHLidan HuYZY. C. ZhuCWChengpeng Wu

Discussion

Loading...

Member takes

Overview

Study reveals distinct metabolites in patients with chronic suppurative otitis media, indicating pathways linked to cholesteatoma.

Key Points

  • Significant differences in metabolites were identified between chronic suppurative otitis media patients with and without cholesteatoma.
  • Non-targeted metabolomics analysis revealed 484 differential metabolites and 32 metabolic pathways linked to chronic suppurative otitis media.
  • The study employed a non-targeted and targeted metabolomics approach to assess tissue samples from 42 patients with chronic suppurative otitis media.
  • Results suggest novel metabolic pathways and metabolites could play important roles in inflammatory processes and bone erosion associated with chronic suppurative otitis media.

Cite This Study

Hu et al. (2025) studied this question.

synapsesocial.com/papers/68c19f9c54b1d3bfb60db473https://doi.org/10.1002/smmd.70015
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Audiometric indicators of cochlear involvement in chronic suppurative otitis media with and without cholesteatoma2026
  2. 2Clinico-microbiological profile and antibiotic sensitivity pattern of chronic suppurative otitis media with cholesteatoma2025
  3. 3Exploring the Link Between Bacterial Biofilm and Disease Severity in Cholesteatoma-Associated CSOM2026 · 2 citations
  4. 4Chronic Suppurative Otitis Media and Cochlear Injury: A Cross-sectional Analysis of Sensorineural Hearing Loss2025 · 3 citations
  5. 5The Systemic Immune Signature of Cholesteatoma: A Comprehensive Cross-Sectional Analysis of Hematological Markers and Clinical Staging2026