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July 3, 2026Medeniyet Medical JournalOpen Access

Exploring the Link Between Bacterial Biofilm and Disease Severity in Cholesteatoma-Associated CSOM

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Authors

MPMarojahan PandianganMGMasyita GaffarRDRiskiana Djamin

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Overview

Cross-sectional study investigates bacterial biofilm's role in disease severity in CSOM cholesteatoma, indicating a need for further research.

Key Points

  • This research aims to explore the relationship between bacterial biofilm and disease severity in chronic suppurative otitis media with cholesteatoma.
  • Cross-sectional study conducted in a tertiary teaching hospital, enrolling patients diagnosed with CSOM cholesteatoma.
  • Bacterial isolates from cholesteatoma tissue were evaluated for biofilm formation using crystal violet staining.
  • Data analyzed using SPSS software.
  • The most frequently identified bacterial species contributed to 42.5% of isolates.
  • 47% of patients presented with severe disease according to the Telmesani grading system.
  • Most bacterial isolates exhibited weak to moderate biofilm production, with no statistically significant correlation established due to limited sample size.

Cite This Study

Pandiangan et al. (2026) studied this question.

synapsesocial.com/papers/6a4750f45c29257aa25786fbhttps://doi.org/10.4274/mmj.galenos.2026.88555
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinico-microbiological profile and antibiotic sensitivity pattern of chronic suppurative otitis media with cholesteatoma2025
  2. 2Bacterial Biofilm in Chronic Suppurative Otitis Media2024
  3. 3Comparison of Germ Patterns between Cholesteatom Tissue and Tympanic Cavum Mucosa Tissue in COSM with Cholesteatom at Dr. Mohammad Hoesin Hospital, Palembang2024
  4. 4Changing Pattern of Cholesteatoma and Granulation Tissue in CSOM with Its Relation to Complications2025
  5. 5Chronic Suppurative Otitis Media: A Prospective Descriptive Study of the Microbiology and Antimicrobial Susceptibility Patterns2024 · 2 citations