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September 10, 2025NutrientsOpen Access

Monounsaturated Fatty Acids in Cardiovascular Disease: Intake, Individual Types, and Content in Adipose Tissue as a Biomarker of Endogenous Exposure

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Narrative review explores the link between monounsaturated fatty acids, adipose tissue biomarkers, and ASCVD risk.

Evidence shows that individual types of monounsaturated fatty acids may impact cardiovascular disease risk differently.
Adipose tissue composition serves as a biomarker of long-term monounsaturated fatty acid exposure, reflecting intake over time.
Guidelines suggest increasing intake of monounsaturated fatty acids, yet recent studies show conflicting evidence regarding their cardiovascular effects.
Research indicates plant-derived monounsaturated fatty acids might provide benefits over those from animal sources.

Pedersen et al. (2025) studied this question.

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