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September 10, 2025Biomedical ReportsOpen Access

Aortitis after granulocyte‑colony stimulating factor administration: A case report

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Aortitis developed after G-CSF administration in a 59-year-old man receiving chemotherapy for liver metastases.
The patient experienced significant fever and elevated C-reactive protein levels, leading to suspicion of febrile neutropenia.
Contrast-enhanced CT scans confirmed aortitis with thickening of the arterial walls, consistent with the diagnosis.
Monitoring post-antibiotic treatment showed improvement, highlighting potential G-CSF complications in chemotherapy patients.

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Case report describes aortitis following granulocyte-colony stimulating factor use in chemotherapy, suggesting potential complications.

Fujiwara et al. (2025) studied this question.

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