What does this research mean for the field?

G-CSF administration during neoadjuvant chemotherapy can be associated with the development of aortic arteritis in patients with breast cancer. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To highlight the occurrence of aortitis following G-CSF administration during breast cancer chemotherapy.

March 16, 2026Nihon Ika Daigaku Igakkai ZasshiOpen Access

A Case of G-CSF-Associated Aortitis during Neoadjuvant Chemotherapy for Breast Cancer

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To highlight the occurrence of aortitis following G-CSF administration during breast cancer chemotherapy.
Case report of a 62-year-old woman with HER2-positive breast cancer.
Patient received pegfilgrastim for febrile neutropenia prophylaxis.
Tracked symptoms and treatment response following G-CSF administration.
Patient developed fever and chest pain 11 days post-G-CSF administration.
Oral levofloxacin treatment did not alleviate the symptoms.
Emergency transportation to the hospital was required due to persisting symptoms.

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Implication

Case report reveals aortic arteritis linked to G-CSF in a breast cancer patient, suggesting potential risks.

Cite This Study

Katayama et al. (2026) studied this question.

synapsesocial.com/papers/69b79dce8166e15b153aafec https://doi.org/10.1272/manms.22.30

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A Case of G-CSF-Associated Aortitis during Neoadjuvant Chemotherapy for Breast Cancer

Key Points

Discussion

Implication

Cite This Study

A Case of G-CSF-Associated Aortitis during Neoadjuvant Chemotherapy for Breast Cancer

Key Points

Discussion

Implication

Cite This Study

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