February 24, 2024CureusOpen Access

Granulocyte-Colony Stimulating Factor (G-CSF)-Induced Aortitis: A Case Report

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Pegylated granulocyte colony-stimulating factor induced acute aortitis with fever and severe arthralgia in a patient receiving chemotherapy for breast cancer.
Computed tomography revealed vascular wall thickening along the aortic arch and descending aorta, accompanied by elevated erythrocyte sedimentation rate.
Case report evaluation showed prompt resolution of symptoms after stopping the causative agent, aiding differentiation from other non-drug forms of aortitis.

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Case report demonstrates pegylated G-CSF-induced aortitis in a breast cancer patient, highlighting drug cessation as key to rapid clinical recovery.

Ito et al. (2024) studied this question.

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Case report demonstrates pegylated G-CSF-induced aortitis in a breast cancer patient, highlighting drug cessation as key to rapid clinical recovery.