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September 10, 2025Journal of Fish Biology

Liver transcriptome profiling of the largemouth bass (Micropterus salmoides) suggests host immunoregulatory mechanism in response to Edwardsiella tarda infection

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Authors

HCHuijuan ChenCFCan FengQZQiyi Zhang

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Overview

RNA sequencing reveals 3198 differentially expressed genes in largemouth bass post-E. tarda infection, suggesting robust immune reactions.

Key Points

  • Largemouth bass demonstrates a significant innate immune response to Edwardsiella tarda infection, indicating important immunoregulatory mechanisms.
  • RNA sequencing identified 3198 differentially expressed genes, with 1765 upregulated and 1433 downregulated genes pivotal to immune response.
  • Enrichment analysis showed significant involvement of pattern recognition receptor signaling pathways and pro-inflammatory cytokines in response to E. tarda.
  • This research provides foundational insights into the immunological responses of largemouth bass to bacterial infections, suggesting further study is needed.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68c1a25a54b1d3bfb60dd12dhttps://doi.org/10.1111/jfb.70138
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