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September 10, 2025International Physical Medicine & Rehabilitation JournalOpen Access

Effect of Cetylated fatty acid supplementation on low back facet joint arthritis

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Authors

AKAnjali KashyapColumbus State Community CollegeAJAnisha JavvajiStony Brook SchoolBCBarry CaplanCalifornia Institute of Technology

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Overview

Observational analysis showed cetylated fatty acid supplementation reduced disability and pain in patients with low back pain, suggesting potential therapeutic benefits.

Key Points

  • CFA supplementation significantly reduced RMDQ scores by about 2.5 points after four weeks, indicating improved physical function.
  • 21.4% of patients experienced skin irritation from the transdermal patch, highlighting the need for monitoring adverse effects.
  • The study included 28 participants, with an average age of 61.8 years, all suffering from axial back pain for over three months.
  • Further studies are required to validate the findings, including larger cohorts and control groups to assess the efficacy of CFA supplementation.

Cite This Study

Kashyap et al. (2025) studied this question.

synapsesocial.com/papers/68c1a5f254b1d3bfb60dfa44https://doi.org/10.15406/ipmrj.2025.10.00399
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of orally administered cetylated fatty acids on symptoms and functional capacity in patients with knee osteoarthritis: results of a randomized, double-blind, placebo-controlled study2025
  2. 2E047 Efficacy and safety of cetylated fatty acids in osteoarthritis: a systematic review and meta-analysis2026
  3. 3Physiotherapy Reduces Pain and Alters Fatty Acid Biomarkers in Women with Chronic Non-Specific Low Back Pain2025 · 1 citations
  4. 4Prospective, non-inferiority, multicenter, randomized, single-blind clinical trial comparing cooled radiofrequency ablation to standard radiofrequency ablation to manage chronic facetogenic lumbar back pain2026 · 1 citations
  5. 5Effectiveness of thermal radiofrequency ablation versus corticosteroid injections for pain reduction in facet-mediated chronic low back pain: a systematic review and meta-analysis2026