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September 10, 2025Journal of Cardiovascular Electrophysiology

Incidence, Predictors, and Outcomes With Ventricular Arrhythmias in Continuous Flow Left Ventricular Assist Device Recipients: A Multicenter Analysis

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Authors

JVJossy VargheseJGJashan GillRMRezwan Munshi

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Overview

Multicenter analysis reveals high VA incidence and increased morbidity in LVAD patients, highlighting potential mortality predictors.

Key Points

  • Patients with pre-LVAD ventricular arrhythmias experienced significantly higher post-implant arrhythmic burden and hospitalizations.
  • Out of 408 LVAD recipients, 254 (62%) had pre-LVAD ventricular arrhythmias, influencing their clinical outcomes.
  • Kaplan-Meier analysis indicated no significant difference in overall mortality between patients with and without prior VAs.
  • Multivariate analyses identified left ventricular end-diastolic dimension as the only independent predictor of mortality.

Cite This Study

Varghese et al. (2025) studied this question.

synapsesocial.com/papers/68c1a5ff54b1d3bfb60e015ehttps://doi.org/10.1111/jce.70033
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Ventricular Arrhythmia Ablation in Patients With Heart Mate II Left Ventricular Assist Devices: An Evaluation of Ablation Therapy2016 · 30 citations
  2. 2Characteristics of Ventricular Tachycardia Ablation in Patients With Continuous Flow Left Ventricular Assist Devices2015 · 103 citations
  3. 3Validation of Novel 3-Dimensional Electrocardiographic Mapping of Atrial Tachycardias by Invasive Mapping and Ablation2013 · 92 citations
  4. 4A Review of New-Onset Ventricular Arrhythmia after Left Ventricular Assist Device Implantation2022 · 18 citations