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September 10, 2025PLoS ONEOpen Access

Assessment of retinal and choroidal structural and microvascular changes in early diabetic retinopathy using swept-source optical coherence tomography angiography

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Authors

JJJin JiangChina Aerodynamics Research and Development CenterXWXiaole WangJiangxi University of Traditional Chinese MedicineHBHongjun BianNantong University

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Overview

Retrospective analysis identifies significant changes in vascular density and choroidal structure in early diabetic retinopathy, highlighting detection potential.

Key Points

  • The NPDR group exhibited a significantly larger FAZ area compared to controls, indicating disease severity.
  • Choroidal vascular index, vascular density, and perfusion area were significantly lower in the NPDR group relative to the NDR group.
  • SS-OCTA effectively monitors structural changes in early diabetic retinopathy, serving as a valuable evaluation tool.
  • As diabetic retinopathy severity increases, distinct vascular changes become evident, emphasizing the need for early detection.

Cite This Study

Jiang et al. (2025) studied this question.

synapsesocial.com/papers/68c1a78154b1d3bfb60e121chttps://doi.org/10.1371/journal.pone.0327770
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of Choroidal Changes in Diabetic Retinopathy2024
  2. 2Longitudinal Changes in Anatomic Biomarkers on Optical Coherence Tomography Angiography in Diabetic Retinopathy2025
  3. 3Optical Coherence Tomography Angiography Findings in Diabetic Retinopathy: A Clinical Comparative Study2025
  4. 4Diagnostic value of choroidal vascular density in predicting the progression of diabetic retinopathy2025 · 1 citations
  5. 5Changes in peripapillary microvasculature and retinal nerve fibre layer in diabetes and diabetic retinopathy using optical coherence tomographic angiography: a community-based, cross-sectional study2025