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September 10, 2025The Egyptian Journal of Neurosurgery : the official publication of the Egyptian Society of Neurological Surgeons/Egyptian journal of neurosurgeryOpen Access

Microvascular tissue transfer in reconstruction of anterior skull base defects secondary to sinonasal malignancies: a case series and proposed reconstructive framework

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Authors

NPNikhil PrasadRajiv Gandhi Cancer Institute and Research Centre KMKripa Shanker MishraRajiv Gandhi Cancer Institute and Research Centre RARajan AroraChildren's Hospital of Michigan

Discussion

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Overview

Case series illustrates microvascular free flap reconstruction of anterior skull base defects in sinonasal malignancy patients, suggesting a reconstructive framework.

Key Points

Microvascular free flap reconstruction successfully managed complex anterior skull base defects in two patients.
In one case, a radial forearm free flap was used to address a recurrent lymphoepithelial carcinoma defect.
An anterolateral thigh free flap was employed for managing defects with cerebrospinal fluid leaks in the second case.
Reconstruction techniques emphasized the importance of addressing complications like infections and prior tissue damage.

Cite This Study

Prasad et al. (2025) studied this question.

synapsesocial.com/papers/68c1aac654b1d3bfb60e3318 https://doi.org/10.1186/s41984-025-00454-1

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September 10, 2025The Egyptian Journal of Neurosurgery : the official publication of the Egyptian Society of Neurological Surgeons/Egyptian journal of neurosurgeryOpen Access

Microvascular tissue transfer in reconstruction of anterior skull base defects secondary to sinonasal malignancies: a case series and proposed reconstructive framework

View Full Paper

Ask AI

Bookmark

Authors

NPNikhil PrasadRajiv Gandhi Cancer Institute and Research Centre KMKripa Shanker MishraRajiv Gandhi Cancer Institute and Research Centre RARajan AroraChildren's Hospital of Michigan

Discussion

Member takes

Overview

Case series illustrates microvascular free flap reconstruction of anterior skull base defects in sinonasal malignancy patients, suggesting a reconstructive framework.

Key Points

Microvascular free flap reconstruction successfully managed complex anterior skull base defects in two patients.
In one case, a radial forearm free flap was used to address a recurrent lymphoepithelial carcinoma defect.
An anterolateral thigh free flap was employed for managing defects with cerebrospinal fluid leaks in the second case.
Reconstruction techniques emphasized the importance of addressing complications like infections and prior tissue damage.

Cite This Study

Prasad et al. (2025) studied this question.

synapsesocial.com/papers/68c1aac654b1d3bfb60e3318 https://doi.org/10.1186/s41984-025-00454-1

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