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November 17, 2025Head & Neck

Microvascular Free Tissue Transfer for Reconstruction of Anterior Skull Base Defects

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Authors

TTThomas G. TownesECEdward I. ChangMSMatheus Sewastjanow-Silva

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Overview

Retrospective analysis shows free flap reconstruction improved outcomes in anterior skull base defects, highlighting the usefulness of multimodality therapy.

Key Points

  • To evaluate the outcomes of microvascular free flap reconstruction for anterior skull base defects in patients with tumors.
  • Retrospective analysis of patients with anterior skull base defects
  • Focus on outcomes of free flap reconstruction
  • Assessment of complications and reconstructive techniques
  • Sixty-three free flap reconstructions performed
  • Open maxillectomy and craniofacial resection as common ablative methods
  • Complications occurred in 33% of patients within 30 days after reconstruction
  • No cases of surgical mortality reported

Cite This Study

Townes et al. (2025) studied this question.

synapsesocial.com/papers/692509eec0ce034ddc352a7ahttps://doi.org/10.1002/hed.70091
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Microvascular tissue transfer in reconstruction of anterior skull base defects secondary to sinonasal malignancies: a case series and proposed reconstructive framework2025
  2. 2Vascularized anterolateral thigh free flap for salvage reconstruction of complex anterior skull base and nasion defects after failed conventional reconstruction- how I do it.2026
  3. 3Reconstructing the Anterior Skull Base After Oncologic Resection: A Comprehensive Systematic Review of Open Techniques and Outcomes2026
  4. 4International Session 28　　Skull base 12026
  5. 5Outcomes of Free Flap Soft Tissue Reconstruction for Skull Base Defects: A Systematic Review and Meta-Analysis2026