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September 10, 2025British Poultry Science

Pharmacokinetics, plasma protein binding and bioavailability of Ketoprofen in Pekin ducks after different routes of administration

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Authors

OÇOrhan ÇorumHOH. OğuzTETeslime Erdoğan

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Overview

Study reveals the bioavailability and pharmacokinetics of ketoprofen in Pekin ducks, suggesting IM is superior to oral administration.

Key Points

  • IV ketoprofen shows rapid clearance and small distribution volume in Pekin ducks.
  • IM administration achieves higher peak plasma concentrations compared to oral routes (13.82 μg/ml vs. 6.76 μg/ml).
  • Bioavailability of ketoprofen is higher after IM (106%) versus oral (63%) administration in ducks.
  • Findings assist in establishing proper dosage regimens for anti-inflammatory treatments in Pekin ducks.

Cite This Study

Çorum et al. (2025) studied this question.

synapsesocial.com/papers/68c1ad5c54b1d3bfb60e574chttps://doi.org/10.1080/00071668.2025.2525518
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Also Consider

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  1. 1Pharmacokinetics of Tolfenamic Acid Administered Orally and Intravenously at Different Doses in Pekin Ducks (Anas platyrhynchos domestica)2025
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