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September 10, 2025Ibom Medical JournalOpen Access

Detection of Early Onset Nephropathy in Children with Sickle Cell Anaemia in Calabar, Nigeria Using Microalbuminuria

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Authors

UCUzomba CIUniversity of CalabarNENsa EIUniversity of Cross River StateBEB P Sim esUniversity of Calabar

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Implication

Cross-sectional study found 25% prevalence of nephropathy in children with sickle cell anaemia, highlighting the need for early screening.

Key Points

  • Microalbuminuria prevalence was 25% among children with sickle cell anaemia in Calabar, Nigeria.
  • Urine albumin/creatinine ratio showed a significant negative correlation with steady state packed cell volume.
  • Cross-sectional study of 80 children aged 2 to 16 with sickle cell anaemia was conducted for data collection.
  • The findings support the need for early screening of microalbuminuria to detect nephropathy in this population.

Cite This Study

CI et al. (2025) studied this question.

synapsesocial.com/papers/68c1afc054b1d3bfb60e7533https://doi.org/10.61386/imj.v18i3.715
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early Detection of Renal Complication in Children With Sickle Cell Disease: A Single Center Prospective Study2024
  2. 2Prevalence and Pattern of Kidney Disease among Patients with Sickle Cell Anaemia at a Tertiary Health Facility in Northeastern Nigeria2024
  3. 3Persistent proteinuria among a cohort of Nigerian children with sickle cell anaemia2026
  4. 4Early glomerular and tubular dysfunction in children with sickle cell disease2026
  5. 5Albuminuria and associated renal and hemodynamic factors in adults with steady-state sickle cell disease: a multicenter study with measured GFR2026