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The final stage: Investigating determinants of plasmin generation in the third trimester of pregnancy

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Observational analysis indicates maternal age impacts D-dimer and PAP complex levels, suggesting key implications for fibrinolysis in late pregnancy.

Mean D-dimer levels were significantly correlated with maternal age, gestational age, and BMI grouping.
With each advancing year of maternal age, D-dimer levels increased by 2.0 ng/mL, indicating a notable trend.
PAP complex levels rose by 0.8 ng/mL with increasing maternal age, suggesting its critical role in plasmin generation.
Findings emphasize the need for age consideration when interpreting plasma indicator values in pregnant women.

Okoye et al. (2025) studied this question.

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Observational analysis indicates maternal age impacts D-dimer and PAP complex levels, suggesting key implications for fibrinolysis in late pregnancy.