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September 10, 2025Current Nanomedicine

Development of Mucopenetrating Pegylated Liposomes Functionalized with Sodium Taurocholate for Enhanced Oral Insulin Delivery

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Authors

AVAkash VikalRMRashmi MauryaBKBalak Das Kurmi

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Overview

Novel oral insulin system using PEGylated liposomes improves bioavailability and efficacy, suggesting a non-invasive alternative.

Key Points

  • Novel oral insulin formulation improves bioavailability and enhances insulin delivery.
  • In vivo studies showed significant therapeutic efficacy in diabetic animal models.
  • PEGylated liposomal technology protects insulin from degradation in the gastrointestinal tract.
  • Sodium taurocholate modulates intestinal permeability, facilitating better absorption.

Cite This Study

Vikal et al. (2025) studied this question.

synapsesocial.com/papers/68c1b1a154b1d3bfb60e9509https://doi.org/10.2174/0124681873388393250725051331
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