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September 10, 2025Journal of Experimental OrthopaedicsOpen Access

Effect of corticosteroids and hyaluronic acid injections on knee osteoarthritis trajectory

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Authors

ABAlessandro BensaLPLuca Bianco PrevotGPG. Peretti

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Overview

Observational study compares corticosteroids and hyaluronic acid injections in knee OA patients, highlighting distinct outcomes.

Key Points

  • Corticosteroids showed clinically relevant short-term benefits for knee OA compared to hyaluronic acid.
  • Both treatment groups did not experience overall worsening of knee osteoarthritis after 36 months.
  • Hyaluronic acid was associated with long-term functional improvement in knee OA symptoms.
  • No significant differences were found in joint space narrowing progression or the need for knee arthroplasty between treatments.

Cite This Study

Bensa et al. (2025) studied this question.

synapsesocial.com/papers/68c1b61454b1d3bfb60eb79fhttps://doi.org/10.1002/jeo2.70333
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