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August 1, 2025International Journal of NanomedicineOpen Access

Role of SIRT1-mediated mitochondrial and Akt pathways in glioblastoma cell death induced by Cotinus coggygria flavonoid nanoliposomes [Retraction]

Gang Wang Jun Jie Wang Shing Shun Tony To Heyang Zhao Jing Wang Hongming Tang

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Key Points

SIRT1-mediated pathways contribute to glioblastoma cell death in response to flavonoid nanoliposomes.
Cell death induction linked to both mitochondrial and Akt pathways was observed.
Experimental evidence demonstrated the role of Cotinus coggygria in targeting these pathways.
Retraction emphasizes the need for rigorous validation in glioblastoma research.

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Implication

Findings reveal SIRT1 and mitochondrial pathways impact glioblastoma cell death, suggesting potential therapeutic strategies.

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Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c1b81254b1d3bfb60ec091 https://doi.org/10.2147/ijn.s557134

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